Southeast Asia is both a source and victim of plastic pollution in the Pacific Ocean, including the South China Sea, peripheral seas and rivers. Countries in the region are major contributors to land-based plastic waste leaking into the world’s oceans. Around 80 percent of marine plastic debris can be traced back to land-based plastic waste. Southeast Asia and the broader East Asia region are facing the toughest challenge in this regard. This research analyses national and regional efforts to address plastic pollution in Southeast Asia. It explores the contributions of governments, regional bodies, scientists, the private sector, local communities and civil society organisations to finding solutions to plastic pollution in the region. This research also examines the multisectoral approach and human security approach to marine environmental issues and plastic pollution.